The Black Queen is Named Enemy in Borderlands 2. She is located in The Dust region on the Planet Pandora. You have a 33.3% chance to encounter this Rare Spawn near the Church on Booth Hill.
She can also be encountered during the side quest “Claptocurrency” in the “Commander Lilith & the Fight for Sanctuary” DLC, however, her name is then changed to “Dark Web”.
The Black Queen can also spawn twice during the Raid on Digistruct Peak.
You can farm The Black Queen for the Nukem as he is the dedicated loot source for this item. The Black Queen’s legendary item has a 10% drop chance.